Tuesday, February 17, 2009

The Spotless Mind


Believe it or not, Dutch scientists have conducted a research study suggesting that a common heart medicine, beta-blockers, might actually help people banish painful memories.

The researchers induced negative memories on a group of subjects by exposing them to images of spiders accompanied by mild electric shocks. The next day half of the subjects were given a dose of beta-blockers while the others received a placebo pill. When exposed once again to the same spider-shock combo, those subjects who had taken the beta-blockers showed less fear than the control group, even after the effects of the meds had worn off.

They had not forgotten the spiders or electric shocks of the previous day, but somehow the negative aspects of their memories had diminished.

How is this possible? One hypothesis rests on the intricate process by which we recall memories:
"Each time a memory is recalled it changes a little, and the new version is recorded in the long-term memory stash via brain chemical fluctuations in a process called reconsolidation. The beta-blockers could interfere with [certain other] brain chemicals, blocking reconsolidation of the emotional component of the memory, but leaving the rest of the memory intact."
So, in a sense, no memory is truly being erased -- though sensationalism sells, as do parallels to Gondry movies starring Kate Winslet. But then again, what's left when we erase the content of our memories? A bunch of empty facts that, stripped of their emotional relevance, will likely be truly forgotten soon after.

For more on these experiments, check out these articles from BBC News and Discovery Magazine.